Sunday, March 31, 2013

Are you being persecuted?

If he actually existed, then yes, they persecuted the shit out of him

If he actually existed, then yes, they persecuted the bejesus out of him

The Daily Mash presents a simple questionnaire to help you work out how persecuted you are:

Are you excluded from high office, such as being prime minister or the Queen, because of your religion?

Are you completely excluded from society even though you believe in miracles?

Are you prevented from worshipping in, let?s say, a church, on, let?s say, a Sunday morning?

Are you prevented from constantly judging complete strangers?

Are you prevented from sticking your nose into other people?s personal lives?

Do you believe that Lord Carey was elected to the House of Lords?

Does the Today programme ban you from boring the shit out of everyone with two minutes of sanctimonious drivel every morning?

Are schools, funded largely by people who do not share your views, banned from telling children about your favourite miracles?

Has an organisation, funded largely by people who do not share your views, stopped making Songs of Praise?

Do some of the country?s biggest newspapers ignore you whenever you object to the slightest little thing?

Does Britain celebrate Christmas because it is the birthday of Isaac Newton?

Are you currently enjoying a long weekend to commemorate the untimely death of Judy Garland?


So, are you being persecuted?

All ?yes?: Britain does not celebrate Christmas because it is the birthday of Isaac Newton. You may actually benefit from some light persecution.

Mostly ?yes?: Perhaps this really is the time of year when you commemorate? Judy Garland. That is deeply fabulous of you. You?re not being persecuted as much as you used to.

50-50: You?re probably always ?50-50? in these kinds of things. You might want to shake it up a bit.

Mostly ?no?: You are probably a Roman Catholic and are subject to some persecution, but only if you really want to be the Queen.

All ?no?: You are an Anglican Christian and you are not being persecuted. Congratulations!

Source: http://www.thedailymash.co.uk/news/society/are-you-being-persecuted-2013033064361

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Gene Simmons says music can save a child's life

Gene Simmons, the lead singer of the rock band Kiss, makes an unannounced appearance at a fundraiser concert at the Brennan Rock & Roll Academy, Saturday, Mar. 30, 2013, in Sioux Falls, S.D. (AP Photo/Dirk Lammers)

Gene Simmons, the lead singer of the rock band Kiss, makes an unannounced appearance at a fundraiser concert at the Brennan Rock & Roll Academy, Saturday, Mar. 30, 2013, in Sioux Falls, S.D. (AP Photo/Dirk Lammers)

Gene Simmons, the lead singer of the rock band Kiss, makes an unannounced appearance at a fundraiser concert at the Brennan Rock & Roll Academy, Saturday, Mar. 30, 2013, in Sioux Falls, S.D. (AP Photo/Dirk Lammers)

(AP) ? Kiss frontman Gene Simmons made a surprise appearance at a Sioux Falls benefit concert Saturday, where he spoke of music's power to positively shape children's lives.

Simmons's appearance came on the final day of a week of concerts to benefit the music academy for Sioux Falls Boys & Girls Clubs members.

"This is about kids. We've had our chance. We've got to give them a chance. Anything that gets them off the street is a good thing," Simmons said.

Music, Simmons said, is self-empowering.

"It doesn't matter if you become a star. If you don't believe in yourself and get up on stage, everybody is watching. You can feel the power ... and it helps you get through life, especially when you're impressionable."

He said getting involved in music ? whether it's learning to play an instrument or sing karaoke ? improves social skills, too.

Motley Crue singer Vince Neil was also at Saturday's show, and he, too, expounded on the positive benefits of music.

"Say you finish your first song, it could be 'Mary Had a Little Lamb,' it doesn't matter, but at least it's something you've played," Neil said. "And I think for kids, they could go into a whole other direction because they accomplished something."

Neil said he was 10 when he first started taking guitar lessons.

"I was terrible," he said laughing. "That's why I'm not a guitarist. I went into the other direction."

___

Follow Kristi Eaton on Twitter at http://twitter.com/kristieaton .

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/4e67281c3f754d0696fbfdee0f3f1469/Article_2013-03-30-People-Gene%20Simmons/id-d9e4119219e94fa6ba94e958f4cf49cd

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Verizon's Vehicle Diagnostics by Delphi now monitoring your car for $250

Verizon's Vehicle Diagnostics by Delphi now monitoring your car for $250

Who'd have thought we'd be happy to see an unassuming black box? Delphi and Verizon managed to whet our interest with their Vehicle Diagnostics kit and service at CES, and our curiosity is renewed now that the monitoring combo is available for drivers. The finished product costs a fairly steep $250 for the Delphi adapter, although it does deliver two years of free service and costs a contract-free $5 per month afterwards. Shelling out brings the promised remote troubleshooting and notifications, including alerts for any performance problems and warnings for any geofencing violations. If you're willing to pair an Android or iOS phone with the kit over Bluetooth, you can also use the smart device in place of your keys -- temporarily, we hope. Vehicle Diagnostics should work with most cars made from 1996 onward, but do some homework before any outlay: at least a few cars miss out on the full diagnostic suite, which might dampen dreams of a connected car utopia.

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Job Opportunity: Reference Coordinator (Canadian Museum of ...

Job Opportunity: Reference Coordinator (Canadian Museum of Immigration at Pier?21)

Posted by CLA Govt Library and Info Mgmt Professionals Network on 2013/03/30

Canadian Museum of Immigration at Pier 21

Reference Coordinator (Bilingual) ? 2 Positions

Reports to: Reference Services Manager
Grade: 3
Duration: 12 month contract position

Purpose of Position

This position requires a high level of enthusiasm and dedication to customer service with the ability to multitask in a busy library environment. Strong problem-solving skills, analytical skills and attention to detail are a must. Interest in genealogy and/or history is an asset.

Reporting to the Reference Services Manager, the Reference Coordinator will work with the Museum?s visitors to locate, authenticate and analyse a variety of records related to immigration and genealogy. This includes books, databases, periodicals, and a wide variety of digital and hard copy sources including the Museum?s story and image collections.

The Reference Coordinator provides comprehensive reference services including conducting reference interviews; responding to reference inquiries using computerized information retrieval services and manual sources; serving the daily visitors to the Scotiabank Family History Centre as well as those who write, call and email; helping select materials for inclusion in the reference collection and cataloguing acquisitions; and assisting in determining areas that require strengthening.

Essential Position Functions

The Reference Coordinator will:

  • Respond to public research requests (onsite, by telephone, mail and email) through online research, databases, books and microfilm
  • Photocopy, file and scan
  • Edit and print digital files
  • Catalogue new acquisitions
  • Help with data entry
  • Maintain proper care and maintenance of all documents handled
  • Create finding aids (indexes, catalogues, etc.)
  • Assist with new staff orientation and train seasonal staff and volunteers
  • Maintain visitation statistics for the Scotiabank Family History Centre
  • Help resolve visitor concerns and complaints
  • Be responsible for Scotiabank Family History Centre daily cash reconciliation
  • Attend orientation sessions and complete training readings
  • Assist with other duties as assigned by the Reference Services Manager

Education, Knowledge & Experience

Skills and Qualifications ?Required

  • Bachelor?s degree or certificate in related discipline such as museum or library studies
  • This position requires the use of both Official Languages (French/English) written and verbal
  • Experience in the customer service industry, ideally a museum or library
  • Demonstrated ability to develop good working relationships with team members
  • Outgoing personality with excellent written and verbal communication skills
  • High level of customer service skills
  • Demonstrated research skills: abilities in locating, evaluating, analyzing and synthesizing large amounts of historical information from diverse sources
  • Experience working within a high traffic environment either within a museum, library and/or customer service position
  • Strong attention to detail and excellent organizational skills: ability to plan, organize, prioritize and meet deadlines
  • Demonstrated ability to take initiative and work with minimum supervision and to develop working relationships with all members of the organization creating a strong team environment
  • Initiative and judgment in determining the extent of visitor information needs

Skills and Qualifications ? Desired

  • Knowledge of Canadian immigration patterns and history
  • Substantial knowledge and experience in the field of genealogy
  • Knowledge of Adobe Photoshop, Microsoft Access and basic scanning procedures an asset
  • Proficiency in additional languages beyond Canada?s official languages

Working Conditions & Physical Demands

  • Busy library environment
  • Requires long periods at a desk and time in front of a computer
  • Willingness to work irregular hours, overtime, weekends and/or statutory holidays and provincial/territorial holidays, when required
  • Willingness to wear a Canadian Museum of Immigration at Pier 21 uniform

Compensation for this position is commensurate with experience and includes a comprehensive benefit package.

If you are interested in this opportunity please send a resume and a cover letter to Cara MacDonald, Reference Services Manager, at caramacdonald@pier21.ca

Competition closes at 5 p.m. on Friday, April 5th, 2013.

We thank all applicants for their interest. However, only those selected for an interview will be contacted. Top candidates shortlisted for an interview may be required to take a French or English language proficiency test.

The Canadian Museum of Immigration at Pier 21 is committed to the principles of Employment Equity and to achieving a workforce which is representative of the Canadian population. We strongly encourage candidates to self-identify if they are a woman, an Aboriginal person, a member of a visible minority group or a person with a disability.

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Source: http://clagov.wordpress.com/2013/03/30/job-pier-21/

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Researchers engineer plant cell walls to boost sugar yields for biofuels

Mar. 29, 2013 ? When blessed with a resource in overwhelming abundance it's generally a good idea to make valuable use of that resource. Lignocellulosic biomass is the most abundant organic material on Earth. For thousands of years it has been used as animal feed, and for the past two centuries has been a staple of the paper industry. This abundant resource, however, could also supply the sugars needed to produce advanced biofuels that can supplement or replace fossil fuels, providing several key technical challenges are met.

One of these challenges is finding ways to more cost-effectively extract those sugars. Major steps towards achieving this breakthrough are being taken by researchers at the U.S. Department of Energy (DOE)'s Joint BioEnergy Institute (JBEI).

"Through the tools of synthetic biology, we have engineered healthy plants whose lignocellulosic biomass can more easily be broken down into simple sugars for biofuels," says Dominique Loque, who directs the cell wall engineering program for JBEI's Feedstocks Division. "Working with the model plant, Arabidopsis, as a demonstration tool, we have genetically manipulated secondary cell walls to reduce the production of lignin while increasing the yield of fuel sugars."

JBEI is a scientific partnership led by Lawrence Berkeley National Laboratory (Berkeley Lab) whose mission is to advance the development of next generation biofuels that can provide the nation with clean, green and renewable transportation energy that will create jobs and boost the economy. Loque and his research group have focused on reducing the natural recalcitrance of plant cell walls to give up their sugars. Unlike the simple starch-based sugars in corn and other grains, the complex polysaccharide sugars in plant cell walls are locked within a robust aromatic polymer called lignin. Setting these sugars free from their lignin cage has required the use of expensive and environmentally harsh chemicals at high temperatures, a process that helps drive production costs of advance biofuels prohibitively high.

"By embedding polysaccharide polymers and reducing their extractability and accessibility to hydrolytic enzymes, lignin is the major contributor to cell wall recalcitrance," Loque says. "Unfortunately, most efforts to reduce lignin content during plant development have resulted in severe biomass yield reduction and a loss of integrity in vessels, a key tissue responsible for water and nutrient distribution from roots to the above-ground organs."

Lignin has also long posed problems for pulping and animal feed. To overcome the lignin problem, Loque and his colleagues rewired the regulation of lignin biosynthesis and created an artificial positive feedback loop (APFL) to enhance secondary cell wall biosynthesis in specific tissue. The idea was to reduce cell wall recalcitrance and boost polysaccharide content without impacting plant development.

"When we applied our APFL to Arabidopsis plants engineered so that lignin biosynthesis is disconnected from the fiber secondary cell wall regulatory network, we maintained the integrity of the vessels and were able to produce healthy plants with reduced lignin and enhanced polysaccharide deposition in the cell walls," Loque says. "After various pretreatments, these engineered plants exhibited improved sugar releases from enzymatic hydrolysis as compared to wild type plants. In other words we accumulated the good stuff -- polysaccharides -- without spoiling it with lignin."

Loque and his colleagues believe that the APFL strategy they used to enhance polysaccharide deposition in the fibers of their Arabidopsis plants could be rapidly implemented into other vascular plant species as well. This could increase cell wall content to the benefit of the pulping industry and forage production as well as for bioenergy applications. It could also be used to increase the strength of cereal straws, reducing crop lodging and seed losses. Since regulatory networks and other components of secondary cell wall biosynthesis have been highly conserved by evolution, the researchers feel their lignin rewiring strategy should also be readily transferrable to other plant species. They are currently developing new and even better versions of these strategies.

"We now know that we can significantly re-engineer plant cell walls as long as we maintain the integrity of vessels and other key tissues," Loque says.

A paper describing this research in detail has been published in Plant Biotechnology Journal. The paper is titled "Engineering secondary cell wall deposition in plants." Loque is the corresponding author. Co-authors are Fan Yang, Prajakta Mitra, Ling Zhang, Lina Prak, Yves Verhertbruggen, Jin-Sun Kim, Lan Sun, Kejian Zheng, Kexuan Tang, Manfred Auer and Henrik Scheller.

This research was supported by the DOE Office of Science.

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Story Source:

The above story is reprinted from materials provided by DOE/Lawrence Berkeley National Laboratory.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. Fan Yang, Prajakta Mitra, Ling Zhang, Lina Prak, Yves Verhertbruggen, Jin-Sun Kim, Lan Sun, Kejian Zheng, Kexuan Tang, Manfred Auer, Henrik V. Scheller, Dominique Loqu. Engineering secondary cell wall deposition in plants. Plant Biotechnology Journal, 2013; 11 (3): 325 DOI: 10.1111/pbi.12016

Note: If no author is given, the source is cited instead.

Disclaimer: Views expressed in this article do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_environment/~3/VnUOT6b1alA/130329161247.htm

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Late equalizer boosts LA

It?s still troubling to see all those empty seats at BMO Field, once the gold standard in passionate MLS support.

Hopefully the fans who have abandoned TFC (or stashed their scarves for the time being) will recognize that a better product can be found these days along Exhibition Place, where Ryan Nelsen has the Reds organized and working hard for one another.

Unfortunately, Nelsen and his side still have miles to go in terms of getting the personnel where it needs to be, and in teaching the team how to manage matches and situations.

We saw it all there Saturday as TFC gave up an early goal, rallied to take a lead and held that margin until stoppage time. But a mistake in the back gave young Galaxy attacker Jose Villareal a chance to demonstrate his opportunism and his athleticism.

His late goal was the equalizer in a 2-2 draw at BMO Field.

Here are a few quick thoughts, followed by the highlights.

  • Richard Eckersley, once a right back, then a center back and then a right back again ? he?s now apparently a left back.
  • ?We?ve mentioned before about how TFC still needs more quality in several areas, something club president Kevin Payne is presumably addressing. One is right I the middle of the park, where TFC were clearly outmanned over stretches Saturday. Juninho and Marcelo Sarvas ? good MLS midfield men, but not great ? mostly had their way through the center.
  • Donovan (pictured from Satruday)? Meh. Then again, what did we expect? Getting him on the field was about elevating his fitness, as much as anything.

(MORE: Landon Donovan back on field for LA Galaxy)

  • TFC was just not a bit creative for most of Saturday afternoon. Luis Silva?s second-half introduction helped (and a clever little something surely helped on TFC?s second goal), but the Reds need more imagination. So far, too many of the TFC goals tends to rise out of Robert Earnshaw?s opportunism.
  • Hard to say what TFC defender Darel Russell might have been thinking with a ?clearing? header that he put right back in front of his own goal in stoppage time. Anywhere else and the Reds probably get all three points. A draw against the champs, even at home, isn?t terrible for TFC. But conceding a late equalizer (losing two points in the process) is a real bummer, and surely feels like a loss for Nelsen and Co.

Highlights of Saturday?s match:

Source: http://prosoccertalk.nbcsports.com/2013/03/30/thoughts-and-highlights-on-toronto-la-galaxy-draw/related/

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Saturday, March 30, 2013

Nerds vs. Hipsters: Reddit Photo Explains It All

A lot of people describe themselves as nerds these days who really aren't. They're hipsters. But if you have a hard time differentiating, no one can blame you as there are plenty of similarities. Nevertheless, there are a few hipster tells.

Redditor moson posted this helpful image that clearly outlines the differences between nerds and hipsters. Fun fact: the original photo is of actual, honest-to-god scientist nerds from Poland. Hooray!

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Via Reddit

Also on HuffPost:

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Source: http://www.huffingtonpost.com/2013/03/30/nerds-vs-hipsters-reddit_n_2985070.html

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3 of 4 reptiles stolen from Calif. museum found

(AP) ? A Central California science museum has recovered three of four reptiles stolen in a burglary caught on surveillance video, and arrested a suspect in the heist.

The Discovery Center's education coordinator Ian Goudelock says a 3 1/2-foot savannah monitor lizard, red-tailed boa constrictor and a ball python are back at the Fresno museum on Friday. A 3-foot-long ball python remains missing.

The suspect broke into the museum on Wednesday night or Thursday morning, smashed the tanks that held the four reptiles and made off with them in a garbage bag. The suspect also went into the center's gift shop and stole children's toys, the phone system and the security monitor.

Fresno police says they made an arrest on suspicion of the burglary, but the suspect's name was not immediately available.

___

Information from: The Fresno Bee, http://www.fresnobee.com

Source: http://hosted2.ap.org/APDEFAULT/aa9398e6757a46fa93ed5dea7bd3729e/Article_2013-03-29-Reptiles%20Stolen/id-5f8bf82f45064db8a442040dcedff2d9

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Little Cyprus thumbs its nose at EU 'bullies'

Two men walk in the old city of the capital Nicosia, on Friday, March 29, 2013. Banks in Cyprus are open for normal business for the second day, but with strict restrictions on how much money their clients can access, after being shut for nearly two weeks.(AP Photo/Petros Giannakouris)

Two men walk in the old city of the capital Nicosia, on Friday, March 29, 2013. Banks in Cyprus are open for normal business for the second day, but with strict restrictions on how much money their clients can access, after being shut for nearly two weeks.(AP Photo/Petros Giannakouris)

A man walks past graffiti in capital Nicosia, on Friday, March 29, 2013. Banks in Cyprus are open for normal business for the second day, but with strict restrictions on how much money their clients can access, after being shut for nearly two weeks.(AP Photo/Petros Giannakouris)

A Greek Cypriot soldier walks at the old town of the capital Nicosia, on Friday, March 29, 2013. Banks in Cyprus are open for normal business for the second day, but with strict restrictions on how much money their clients can access, after being shut for nearly two weeks.(AP Photo/Petros Giannakouris)

A man with shopping bags and a tourist pass at the old city the capital Nicosia, Cyprus, on Friday, March 29, 2013. Banks in Cyprus are open for normal business for the second day, but with strict restrictions on how much money their clients can access, after being shut for nearly two weeks to prevent people from draining their accounts as the country's politicians sought a way out of an acute financial crisis. (AP Photo/Petros Karadjias)

Private security officers stand at a main door of a bank as people wait outside of a cooperative bank in capital Nicosia, Cyprus, on Friday, March 29, 2013. Banks in Cyprus are open for normal business for the second day, but with strict restrictions on how much money their clients can access, after being shut for nearly two weeks to prevent people from draining their accounts as the country's politicians sought a way out of an acute financial crisis. (AP Photo/Petros Karadjias)

(AP) ? The moment word broke that Cypriot lawmakers in Parliament had voted down a bailout deal that would have raided everyone's savings to prop up a collapsing banking sector, a huge cheer rose up from hundreds of demonstrators gathered outside that echoed through the building's corridors.

Many relished it as a kind of David-against-Goliath moment ? a country of barely a million people standing up to the will of Europe's behemoths who wanted it to swallow a very bitter pill to fix its broken-down economy.

"Shame on Europe for trying to snatch people's savings. It's a mistaken decision that will have repercussions on other economies and banking systems," said protester Panayiotis Violettis. "People have stopped trusting the EU which should be our protector."

Fighting back is not a new experience for Cypriots. From the 1950s guerrilla war against British rule to Greek Cypriots' defiant refusal in 2004 to accept a U.N.-backed peace plan to reunite the island, they are used to holding their own against big opponents.

Just as quickly as Cyprus' euro area partners decided that a deposit grab was the only way out, so Cypriots decided their tiny island was ground zero in Europe's new financial scorched earth policy and that it had to be resisted at all costs.

"Better die on your feet than live on your knees," one placard among the throngs of protesters read. Another said: "It starts with us, it ends with you" as a warning to other Europeans that their savings were no longer safe.

Politicians seized on the public mood. "This is another form of colonization," Greens lawmaker Giorgos Perdikis spouted in Parliament. "We won't allow passage of something that essentially subjugates the Cypriot people for many, many generations.

"Unfortunately, instead of support and solidarity, our partners offered blackmail and bitterness," said Parliamentary Speaker Yiannakis Omirou. The indignant leader of the country's Orthodox Christian Church, Archbishop Chrysostomos II, added: "This isn't the Europe that we believed in when we joined. We believed we would receive some kind of help, some support."

The country's foreign minister, Ioannis Kasoulides, even acknowledged that Cypriot negotiators had contemplated exiting the euro instead of accepting their euro area partners' terms.

In the end, Cyprus accepted a deal that would safeguard small savers but where depositors with more than 100,000 euros in the country's two most troubled banks would lose a big chunk of their money.

Nonetheless, Europe was stunned at the sheer brazenness. How could a pipsqueak country on Europe's fringes thumb its nose to continental juggernauts Germany and France and dare to turn down a deal meant to save it from economic chaos?

It's not the first time the country has pushed back in defiance, even against what many would consider as insurmountable odds. The island's majority Greek Cypriots fought former colonial ruler Britain to a draw in a four-year guerrilla campaign in the 1950s that aimed for union with Greece. That conflict ended in the country's independence in 1960.

Just 14 years later, a Turkish invasion prompted by an abortive coup by supporters of union with Greece resulted in the island's division into an internationally recognized, Greek-speaking south and a breakaway, Turkish-speaking north.

The invasion and its fallout remains an existential matter in the minds of Cypriots and it still informs many of the political and economic decisions the country and its people make.

"Greek Cypriots lost nearly everything during the 1974 invasion," said University of Cyprus History Professor Petros Papapolyviou. "So they reason, what else do we have to lose? Why accept another injustice?"

In 2004, Greek Cypriots again defied international expectations when they voted down a United Nations-backed reunification plan they believed was unfairly weighted against them.

A few days later, the island joined the European Union and some EU leaders were left fuming at what they saw as Greek Cypriot deceit for promising to sign up to a peace deal in exchange for EU membership.

Nearly a decade later and European acrimony at the Cypriot "no" hasn't entirely dissipated. German Finance Minister Wolfgang Schaueble told the Sunday edition of German newspaper Welt am Sonntag that "Cyprus was admitted to the EU in hopes that the plan of then-U.N. Secretary General Kofi Annan to overcome the (island's) divide would be honored."

"I interpret (that) as indicating a sense of vindictiveness rather than rational, result-oriented thinking." said University of Cyprus Associate Professor Yiannis Papadakis.

Were the tough bailout terms some sort of belated punishment? Whether that's true or not, such notions only feed a Cypriot proclivity for conspiracy theories. As in other small, insular societies, threats ? real or imagined ? sharpen a sense of collective victimhood.

Papadakis said Cypriots see their political culture as underpinned by personal relationships. Hence their reference to "friends" instead of "allies," which implies a more pragmatic relationship.

"That's why Greek Cypriots often complain of a 'betrayal from our friends'," he said. But it's wrong for the EU to foist all the blame on Cypriots when things go awry, Papadakis added.

"I believe that the rest of the EU has made a large share of mistakes during this arduous process."

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/3d281c11a96b4ad082fe88aa0db04305/Article_2013-03-30-Defiant%20Cyprus/id-754f946538bb4441803bc67a2ee5b359

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Tetris Blitz to offer deeper, faster take on classic puzzle game

This ain't your daddy's Tetris - get as many rows as you can in two minutes and customize with power-ups

Android Central at GDC

At GDC 2013, we took some time to talk with EA about the latest mobile iteration of the classic puzzle game franchise, Tetris. Tetris Blitz promises to be a whole new experience: there's no failure, just two frantic minutes of dropping blocks and lining up rows as quickly as possible.

read more



Source: http://feedproxy.google.com/~r/androidcentral/~3/XO2eQp090IE/story01.htm

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Famous People Tend to Stay Famous

Discovered:?Get used to Bieber and Kardashian;?a human/Neanderthal love child; DNA tests could predict cancer risks; the intuition of rats.

RELATED: Just a Few Facebook Likes Can Reveal Sexual Orientation

Famous people tend to stay famous. Pop artist Andy Warhol once declared that everyone, at some some point in the future, "would be world-famous for 15?minutes." But according to two professors ? one at McGill, the other at Stony Brook ??true fame is everlasting: "Contrary to popular belief, the people who become truly famous, stay famous for decades." The pair's paper shows that, despite our animosity toward the super-famous ? think Justin Bieber or Kim Kardashian ? they're pretty much here to stay. Why? The authors suggest fame is something of a self-fulfilling prophecy: "Both media and audiences are trapped in a self-reinforcing equilibrium where they must continue to devote attention, airtime, and newspaper space to the same old characters because everyone else does so as well." [American Sociological Review]

RELATED: There's a Two-Headed Bull Shark

Skeletal remains indicate a human/Neanderthal hybrid. We know all about Neanderthals ? a human-like ape species that inhabited west-central Asia and Europe hundreds of thousands of years ago. But until now we didn't know if they ever successfully bred with ancient humans. A skeleton recently discovered in Italy, however, indicates that that at least one female Neanderthal was able to mate with a male human. Still, this doesn't that the populations converged: "Although the hybridization between the two hominid species likely took place, the Neanderthals continued to uphold their own cultural traditions [which] suggests that the two populations did not simply meet, mate and merge into a single group." [NBC Science]

RELATED: Babies Are Evil, Just Like Us

DNA markers portend risk of cancer. A simple test of one's genes could one day predict your risk of cancer. That's the takeaway from a study of 200,000 individuals which indicates that certain markers embedded in one's DNA are routinely associated with a pronounced risk of cancer. It's not so much each marker that's important ? it's the number of them and pattern they form that could indicate a higher propensity to develop cancer. Even though the routine use of these markers is still far out in the future, the medical application is already obvious: "Under certain assumptions, a gene test using all known markers could reduce the number of mammograms and PSA tests by around 20 percent, with only a small cost in cancer cases missed." [Associated Press]

RELATED: Humans Descended from a Tiny Worm

You should trust your intuition. Is pondering useless? In rats, at least, it seems so. A group of researchers in Portugal found that the rodents performed equally well on a series of tasks when given a short time and a long time to decide. "When rats were challenged with a series of perceptual decision problems, their performance was just as good when they decided rapidly as when they took a much longer time to respond. Despite being encouraged to slow down and try harder, the subjects of this study achieved their maximum performance in less than 300 milliseconds." It's yet to be seen whether the results bear on the intuitive faculties of the human race. The researchers are optimistic, though: "Decision-making is not a well-understood process, but it appears to be surprisingly similar among species," one said. [Neuron]

Source: http://news.yahoo.com/famous-people-tend-stay-famous-221855253.html

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Head-on collisions between DNA-code reading machineries accelerate gene evolution

Mar. 28, 2013 ? Bacteria appear to speed up their evolution by positioning specific genes along the route of expected traffic jams in DNA encoding. Certain genes are in prime collision paths for the moving molecular machineries that read the DNA code, as University of Washington scientists explain in this week's edition of Nature.

The spatial-organization tactics their model organism, Bacillus subtilis, takes to evolve and adapt might be imitated in other related Gram-positive bacteria, including harmful, ever-changing germs like staph, strep, and listeria, to strengthen their virulence or cause persistent infections. The researchers think that these mechanisms for accelerating evolution may be found in other living creatures as well.

Replication -- the duplicating of the genetic code to create a new set of genes- and transcription -- the copying of DNA code to produce a protein -- are not separated by time or space in bacteria. Therefore, clashes between these machineries are inevitable. Replication traveling rapidly along a DNA strand can be stalled by a head-on encounter or same-direction brush with slower-moving transcription.

The senior authors of the study, Houra Merrikh, UW assistant professor of microbiology, and Evgeni Sokurenko, UW professor of microbiology, and their research teams are collaborating to understand the evolutionary consequences of these conflicts. The major focus of Merrikh and her research team is on understanding mechanistic and physiological aspects of conflicts in living cells -- including why and how these collisions lead to mutations.

Impediments to replication, they noted, can cause instability within the genome, such as chromosome deletions or rearrangements, or incomplete separation of genetic material during cell division. When dangerous collisions take place, bacteria sometimes employ methods to repair, and then restart, the paused DNA replication, Merrikh discovered in her earlier work at the Massachusetts Institute of Technology.

To avoid unwanted encounters, bacteria orient most of their genes along what is called the leading strand of DNA, rather than the lagging. The terms refer to the direction the encoding activities travel on different forks of the unwinding DNA. Head-on collisions between replication and transcription happen on the lagging strand.

Despite the heightened risk of gene-altering clashes, the study bacteria B. subtilis still orients 25 percent of all its genes, and 6 percent of its essential genes, on the lagging strand.

The scientist observed that genes under the greatest natural selection pressure for amino-acid mutations, a sign of their adaptive significance, were on the lagging strand. Amino acids are the building blocks for proteins. Based on their analysis of mutations on the leading and the lagging strands, the researchers found that the rate of accumulation of mutations was faster in the genes oriented to be subject to head-on replication-transcription conflicts, in contrast to co-directional conflicts.

According to the researchers, together the mutational analyses of the genomes and the experimental findings indicate that head-on conflicts were more likely than same-direction conflicts to cause mutations. They also found that longer genes provided more opportunities for replication-transcription conflicts to occur. Lengthy genes were more prone to mutate.

The researchers noted that head-on replication-transcription encounters, and the subsequent mutations, could significantly increase structural variations in the proteins coded by the affected genes. Some of these chance variations might give the bacteria new options for adapting to changes or stresses in their environment. Like savvy investors, the bacteria appear to protect most of their genetic assets, but offer a few up to the high-roll stakes of mutation.

The researchers pointed out, "A simple switch in gene orientation ?could facilitate evolution in specific genes in a targeted way. Investigating the main targets of conflict-mediated formation of mutations is likely to show far-reaching insights into adaptation and evolution of organisms."

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The above story is reprinted from materials provided by University of Washington, via EurekAlert!, a service of AAAS.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. Sandip Paul, Samuel Million-Weaver, Sujay Chattopadhyay, Evgeni Sokurenko, Houra Merrikh. Accelerated gene evolution through replication?transcription conflicts. Nature, 2013; 495 (7442): 512 DOI: 10.1038/nature11989

Note: If no author is given, the source is cited instead.

Disclaimer: Views expressed in this article do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_environment/~3/S-XGYhm7TK4/130329125307.htm

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North Koreans Rally to Support Threat of Military Strike (Voice Of America)

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Obama to pitch more jobs in public works in Miami

MIAMI (AP) ? President Barack Obama was promoting a plan to create jobs by attracting private investment in highways and other public works during a visit Friday to a Miami port.

The president chose to flesh out details of his proposals in a speech at the port, which is undergoing $2 billion in upgrades paid for with government and private money. Obama, in the quick trip to South Florida, was trying to show that the economy remains his top priority in the midst of high-profile campaigns on immigration reform and gun control.

Among the proposals Obama is calling for:

?$4 billion in new spending on two infrastructure programs that award loans and grants.

?Higher caps on "private activity bonds" to encourage more private spending on highways and other infrastructure projects. State and local governments use the bonds to attract investment.

?Giving foreign pension funds tax-exempt status when selling U.S. infrastructure, property or real estate assets. U.S. pension funds are generally tax exempt in those circumstances. The administration says some international pension funds cite the tax burden as a reason for not investing in American infrastructure.

?A renewed call for a $10 billion national "infrastructure bank" ? a proposal from his first term that gained little traction.

Arriving at the expansive port in Miami, Obama stood inside a double-barreled, concrete-laced hole in the ground, touring a tunnel project that will connect the port to area highways. The project has received loans and grants under the programs Obama is touting and is expected to open next summer.

The president made private-sector infrastructure investment a key part of the economic agenda he rolled out in his State of the Union address last month. He also called in his address for a "Fix-It-First" program that would spend $40 billion in taxpayer funds on urgent repairs.

All of the proposals would require approval from Congress ? no sure bet, considering that House Republicans have shown little appetite for funding Obama's proposed initiatives. In fact, the infrastructure bank is an idea Obama has called for repeatedly before, but it gained little traction during his first term.

Obama's focus on generating more private sector investment underscores the tough road new spending faces on Capitol Hill, where Republican lawmakers often threaten to block additional spending unless it is paid for by tax cuts or other measures. "These are projects that are helpful to the economy and shouldn't break down on partisan lines," said White House spokesman Josh Earnest.

But Florida Republicans, including Gov. Rick Scott, faulted Obama for being "late to the party," arguing ahead of Obama's visit that Florida taxpayers had to pick up too much of the tab because the president was slow to support the project.

White House Council of Economic Advisers Chairman Alan Krueger told reporters traveling with Obama that the initiatives being touted Friday will come to $21 billion, not including the $40 billion for Fix it First. Krueger said any increased spending associated with the proposals would not add to the deficit.

Krueger did not detail how the costs would be paid for, saying only that more information would be included in the president's budget that is scheduled to be released April 10.

___

AP White House Correspondent Julie Pace in Washington contributed to this report.

Follow Josh Lederman on Twitter: http://twitter.com/joshledermanAP

Source: http://news.yahoo.com/obama-pitch-more-jobs-public-works-miami-120516263--finance.html

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FDA OKs first-of-a-kind diabetes drug from J&J

WASHINGTON (AP) ? The Food and Drug Administration says it has approved a first-of-a-kind diabetes drug from Johnson & Johnson that uses a new method to lower blood sugar.

The agency cleared J&J's Invokana tablets for adults with Type 2 diabetes, which affects about 26 million Americans.

The drug is a once-a-day medicine designed to lower blood sugar levels in patients by eliminating more sugar in their urine. The drug works by blocking the reabsorption of sugar by the kidneys, which occurs at higher levels in patients with diabetes.

J&J has touted the drug as the first in a new class of medications to help address the nation's growing diabetes epidemic. The drug differs from older drugs that work by decreasing the amount of sugar absorbed from food and stored in the liver.

Source: http://news.yahoo.com/fda-oks-first-kind-diabetes-drug-j-j-190120185--finance.html

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Picking apart photosynthesis: New insights could lead to better catalysts for water splitting

Mar. 28, 2013 ? Chemists at the California Institute of Technology (Caltech) and the Lawrence Berkeley National Laboratory believe they can now explain one of the remaining mysteries of photosynthesis, the chemical process by which plants convert sunlight into usable energy and generate the oxygen that we breathe. The finding suggests a new way of approaching the design of catalysts that drive the water-splitting reactions of artificial photosynthesis.

"If we want to make systems that can do artificial photosynthesis, it's important that we understand how the system found in nature functions," says Theodor Agapie, an assistant professor of chemistry at Caltech and principal investigator on a paper in the journal Nature Chemistry that describes the new results.

One of the key pieces of biological machinery that enables photosynthesis is a conglomeration of proteins and pigments known as photosystem II. Within that system lies a small cluster of atoms, called the oxygen-evolving complex, where water molecules are split and molecular oxygen is made. Although this oxygen-producing process has been studied extensively, the role that various parts of the cluster play has remained unclear.

The oxygen-evolving complex performs a reaction that requires the transfer of electrons, making it an example of what is known as a redox, or oxidation-reduction, reaction. The cluster can be described as a "mixed-metal cluster" because in addition to oxygen, it includes two types of metals -- one that is redox active, or capable of participating in the transfer of electrons (in this case, manganese), and one that is redox inactive (calcium).

"Since calcium is redox inactive, people have long wondered what role it might play in this cluster," Agapie says.

It has been difficult to solve that mystery in large part because the oxygen-evolving complex is just a cog in the much larger machine that is photosystem II; it is hard to study the smaller piece because there is so much going on with the whole. To get around this, Agapie's graduate student Emily Tsui prepared a series of compounds that are structurally related to the oxygen-evolving complex. She built upon an organic scaffold in a stepwise fashion, first adding three manganese centers and then attaching a fourth metal. By varying that fourth metal to be calcium and then different redox-inactive metals, such as strontium, sodium, yttrium, and zinc, Tsui was able to compare the effects of the metals on the chemical properties of the compound.

"When making mixed-metal clusters, researchers usually mix simple chemical precursors and hope the metals will self-assemble in desired structures," Tsui says. "That makes it hard to control the product. By preparing these clusters in a much more methodical way, we've been able to get just the right structures."

It turns out that the redox-inactive metals affect the way electrons are transferred in such systems. To make molecular oxygen, the manganese atoms must activate the oxygen atoms connected to the metals in the complex. In order to do that, the manganese atoms must first transfer away several electrons. Redox-inactive metals that tug more strongly on the electrons of the oxygen atoms make it more difficult for manganese to do this. But calcium does not draw electrons strongly toward itself. Therefore, it allows the manganese atoms to transfer away electrons and activate the oxygen atoms that go on to make molecular oxygen.

A number of the catalysts that are currently being developed to drive artificial photosynthesis are mixed-metal oxide catalysts. It has again been unclear what role the redox-inactive metals in these mixed catalysts play. The new findings suggest that the redox-inactive metals affect the way the electrons are transferred. "If you pick the right redox-inactive metal, you can tune the reduction potential to bring the reaction to the range where it is favorable," Agapie says. "That means we now have a more rational way of thinking about how to design these sorts of catalysts because we know how much the redox-inactive metal affects the redox chemistry."

The paper in Nature Chemistry is titled "Redox-inactive metals modulate the reduction potential in heterometallic manganese-oxido clusters." Along with Agapie and Tsui, Rosalie Tran and Junko Yano of the Lawrence Berkeley National Laboratory are also coauthors. The work was supported by the Searle Scholars Program, an NSF CAREER award, and the NSF Graduate Research Fellowship Program. X-ray spectroscopy work was supported by the NIH and the DOE Office of Basic Energy Sciences. Synchrotron facilities were provided by the Stanford Synchrotron Radiation Lightsource, operated by the DOE Office of Biological and Environmental Research.

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Story Source:

The above story is reprinted from materials provided by California Institute of Technology. The original article was written by Kimm Fesenmaier.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. Emily Y. Tsui, Rosalie Tran, Junko Yano, Theodor Agapie. Redox-inactive metals modulate the reduction potential in heterometallic manganese?oxido clusters. Nature Chemistry, 2013; 5 (4): 293 DOI: 10.1038/nchem.1578

Note: If no author is given, the source is cited instead.

Disclaimer: Views expressed in this article do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_environment/~3/zABlV4-Gj0A/130329125305.htm

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Friday, March 29, 2013

Ghost Beach 'Piracy' Billboard Asks: What Side Are You On?

Indie band uses high-profile Times Square ad to ask provocative question about music piracy.
By Gil Kaufman



Photo: Ghost Beach

Source: http://www.mtv.com/news/articles/1704535/ghost-beach-piracy-times-square-billboard.jhtml

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Jolie offers answer to latest wedding gossip

By Kurt Schlosser, TODAY

Did Angelina Jolie and Brad Pitt finally get married? It's an answer you've been waiting for since the last time there was a rumor that the two had secretly tied the knot.

Today's rock-solid proof that the A-lister and her betrothed are still just engaged comes from a new TMZ video and a truth-seeking paparazzo in Los Angeles.

"Is that a wedding ring, Angelina?" the voice shouts off camera. "No, it's not," Jolie says through the back of her head as she's ushered into a waiting SUV.

So there you have it. The gold band she was wearing on her left ring finger during a recent humanitarian trip to Africa is still nothing more than just a piece of jewelry. The fact that she actually deemed the question worth answering -- after being with Pitt for 8 years -- strikes us as a bigger deal at this point than her answer.

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Source: http://todayentertainment.today.com/_news/2013/03/28/17502221-angelina-jolie-says-shes-not-wearing-a-wedding-ring?lite

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Forecast: Twitter's ad revenue to double this year

(AP) ? Twitter's ad revenue is believed to be on pace to double this year as the online messaging service delivers more marketing pitches to mobile devices in preparation for a highly anticipated initial public offering of stock.

For now, Twitter remains a privately held company that staunchly refuses to disclose its financial results. That leaves it to research firms tracking Twitter to try to divine how well the 7-year-old company is doing. The estimates are based on a variety of sources, including market trends, ad agencies and other industry data.

Emarketer made its latest educated guess in a Wednesday report that predicted Twitter's worldwide ad revenue will total $583 million this year, up from an estimated $288 million last year. By next year, Twitter will be reeling in nearly $1 billion from ad sales, according to the forecast. The figures don't include the revenue that Twitter gets from licensing agreements that give other companies better access to its database of messages, or tweets.

Twitter, which is based in San Francisco, declined to comment Wednesday.

Although not everyone agrees with eMarketer's calculations, analysts generally concur with the thesis that Twitter's revenue is accelerating at an impressive pace.

"Twitter is becoming a cash machine," said Sam Hamadeh, CEO of PrivCo, a firm that follows privately held companies. "Their growth trajectory is tremendous."

PrivCo predicts Twitter's revenue will total about $520 million this year, up from $245 million last year. Hamadeh said the 2012 figure has been confirmed by reliable sources that he wouldn't name.

The timing of Twitter's IPO is probably of even greater intrigue than the company's financial performance.

Twitter CEO Dick Costolo has repeatedly said that the company isn't under any pressure to go public because it has raised ample financing from investors, including a $400 million injection from venture capitalists in July 2011.

Nevertheless, an IPO is looking more likely during the next year, based on the company's recent efforts to show more advertising into the flow of messages, or tweets, appearing in its users' feeds. Most of the ads are limited to 140-characters, just like non-commercial messages, and are denoted with a "promoted tweet" disclosure.

Twitter's more aggressive pursuit of revenue could be a sign that management is trying to produce financial results more likely to excite prospective investors and drive up the IPO price of its stock. Hamadeh expects Twitter to file its IPO papers late this year, setting up the company to make its stock market debut early next year.

It would probably be the most scrutinized IPO since Facebook went public last May. Facebook hasn't lived up to the hype leading up to its IPO largely because its growth has decelerated since it filed plans to go public. In its most recent quarter, Facebook's revenue rose by 40 percent from the previous year. In the final quarter before its IPO filing, Facebook's revenue rose 55 percent.

If Twitter wants to avoid the same mistake that Facebook made, it will go public while its revenue growth is still widening, Hamadeh said. Some investors also decided to spurn Facebook until it proved its social network will be able to sell more advertising on smartphones and mobile devices without alienating an audience more interested in fraternizing than shopping.

So far, Twitter seems to be prospering from the increasing popularity of mobile devices.

Smartphones and tablets will account for more than half, or $309 million, of Twitter's ad revenue this year, according to eMarketer. By 2015, the research firm expects 60 percent of Twitter's ad revenue to be coming from mobile devices.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/495d344a0d10421e9baa8ee77029cfbd/Article_2013-03-27-Twitter%20Forecast/id-fe59efbcb7f74313a7f11eb29ce3afcd

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gastric bypass gut microbes - Business Insider

Significant changes to the bacteria that live in our guts may be partially behind the rapid weight-loss success of patients who undergo gastric bypass surgery, a new study in mice shows.?

Gastric bypass is a form of weight-loss surgery performed on morbidly obese people. The stomach is made smaller, to about the size of the egg, so that people feel full faster and are not able to eat as much.?

Because gastric bypass is extremely invasive, understanding the mechanisms changing the microbial community in patients' guts after surgery could help scientists design less invasive ways to help dangerously obese people lose weight.?

New?research?published Thursday, March 27, in the journal Science Translational Medicine, suggests that some of the effects of gastric bypass, like decreased weight and body fat, are aided by changes to microbes ? bacteria, viruses, and yes, even fungus ? in everyone's intestines.

To see how gastric bypass affects microbes in the distal gut, which is where the small intestine meets the large intestine, researchers divided obese mice into three of groups: those that received gastric bypass surgery; those that continued to eat a high-fat, high-carb diet; and those that ate a reduced-calorie diet.

Although the bypass mice and those on a restricted diet lost the same amount of weight, the animals who received surgery had changes to their gut bacteria. They showed an increase in bacterial populations associated with healthy, lean humans and a decrease in bacterial populations associated with obese people. Two other groups of bacteria were increased, but their function is still not known.

The gut bacteria of the dieting mice didn't change.

To confirm their results, altered gut microbes from each of the three mice groups were?transferred into the gastrointestinal systems of skinny mice. After two weeks, the mice who received microbes from the mice that had gastric bypass had lost weight, even though they ate the same amount of food as the control mice.

There was no change in weight of the mice who were treated with microbes from either the mice on high-fat diet and the calorie-restricted diet.

This suggests that gastric bypass ? and not calorie restriction or weight loss in general ? triggers these microbial changes. And these changes are one way that gastric bypass causes weight loss.

"Our study suggests that the specific effects of gastric bypass on the microbiota contribute to its ability to cause weight loss and that finding ways to manipulate microbial populations to mimic those effects could become a valuable new tool to address obesity," ?Lee Kaplan, a senior author of the paper, said in a statement.

Source: http://www.businessinsider.com/gastric-bypass-gut-microbes-2013-3

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Jennifer Lawrence afraid of ghosts, not burglars

Fabulous

By Ree Hines, TODAY contributor

Never one to hold back what's on her mind, 22-year-old leading lady Jennifer Lawrence delivered some of her off-the-cuff commentary on a variety of topics -- from feeling like a dog, to the value of a buck, to admitting her biggest fears -- in an interview with U.K. magazine Fabulous.

Maybe her unrehearsed off-screen nature comes from the fact that she just doesn?t know quite what to say without a script.

?I have no control over what comes out of my mouth,? she told the magazine. ?I would probably turn into a mute if I read what I said!?

So she doesn't read or watch or hold back.

?I?m afraid I?m going to go my whole life being scared like a chihuahua,? she said. ?Making movies is where I belong. I shouldn?t be heard just talking. So, when I?m doing movies, I?m really happy. That?s where I?m comfortable, that?s my home. When you put me on a red carpet or on a stage, I turn into chihuahua Jennifer.?

But no matter how much success she has, she doesn't plan to turn into big-spender Jennifer. The "Silver Linings Playbook" star said she was raised to "have respect for money, even though you have a lot of it."

"That?s why mini-bars are difficult, because it?s like yes, I can afford a $6 Snickers bar, but there?s just something wrong with that!" she insisted. "I still drive my same car I?ve been driving for a long time and I haven?t bought a house yet."

As for the house she lives in now, Lawrence shared this shocker: she's not too concerned about uninvited guests -- as long as they're alive.

"I actually get comforted when I feel like there might be a burglar in my house, like, 'There?s a real person that might be breaking into my house, it?s not a ghost, that?s a relief,'" she said.

Related content:

Source: http://todayentertainment.today.com/_news/2013/03/28/17503501-jennifer-lawrence-im-more-scared-of-ghosts-than-burglars?lite

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Thursday, March 28, 2013

Study: Health law to raise claims cost 32 percent

WASHINGTON (AP) ? A new study finds that insurance companies will have to pay out an average of 32 percent more for medical claims on individual health policies under President Barack Obama's health care overhaul.

What does that mean for you?

It could increase premiums for at least some Americans.

If you are uninsured, or you buy your policy directly from an insurance company, you should pay attention.

But if you have an employer plan, like most workers and their families, odds are you don't have much to worry about.

The estimates from the Society of Actuaries could turn into a political headache for the Obama administration at a time when much of the country remains skeptical of the Affordable Care Act.

The administration is questioning the study, saying it doesn't give a full picture ? and costs will go down.

Actuaries are financial risk professionals who conduct long-range cost estimates for pension plans, insurance companies and government programs.

The study says claims costs will go up largely because sicker people will join the insurance pool. That's because the law forbids insurers from turning down those with pre-existing medical problems, effective Jan. 1. Everyone gets sick sooner or later, but sicker people also use more health care services.

"Claims cost is the most important driver of health care premiums," said Kristi Bohn, an actuary who worked on the study. Spending on sicker people and other high-cost groups will overwhelm an influx of younger, healthier people into the program, said the report.

The Obama administration challenged the design of the study, saying it focused only on one piece of the puzzle and ignored cost relief strategies in the law, such as tax credits to help people afford premiums and special payments to insurers who attract an outsize share of the sick.

The study also doesn't take into account the potential price-cutting effect of competition in new state insurance markets that will go live Oct. 1, administration officials said.

At a White House briefing Tuesday, Health and Human Services Secretary Kathleen Sebelius said some of what passes for health insurance today is so skimpy it can't be compared to the comprehensive coverage available under the law. "Some of these folks have very high catastrophic plans that don't pay for anything unless you get hit by a bus," she said. "They're really mortgage protection, not health insurance."

Sebelius said the picture on premiums won't start coming into focus until insurers submit their bids. Those results may not be publicly known until late summer.

Another striking finding of the report was a wide disparity in cost impact among the states.

While some states will see medical claims costs per person decline, the report concluded that the overwhelming majority will see double-digit increases in their individual health insurance markets, where people purchase coverage directly from insurers.

The differences are big. By 2017, the estimated increase would be 62 percent for California, about 80 percent for Ohio, more than 20 percent for Florida and 67 percent for Maryland. Much of the reason for the higher claims costs is that sicker people are expected to join the pool, the report said.

Part of the reason for the wide disparities is that states have different populations and insurance rules. In the relatively small number of states where insurers were already restricted from charging higher rates to older, sicker people, the cost impact is less.

The report did not make similar estimates for employer plans that most workers and families rely on. That's because the primary impact of Obama's law is on people who don't have coverage through their jobs.

A prominent national expert, recently retired Medicare chief actuary Rick Foster, said the report does "a credible job" of estimating potential enrollment and costs under the law, "without trying to tilt the answers in any particular direction."

"Having said that," Foster added, "actuaries tend to be financially conservative, so the various assumptions might be more inclined to consider what might go wrong than to anticipate that everything will work beautifully." Actuaries use statistics and economic theory to make long-range cost projections for insurance and pension programs sponsored by businesses and government. The society is headquartered near Chicago.

Bohn, the actuary who worked on the study, acknowledged it did not attempt to estimate the effect of subsidies, insurer competition and other factors that could offset cost increases. She said the goal was to look at the underlying cost of medical care.

"We don't see ourselves as a political organization," Bohn added. "We are trying to figure out what the situation at hand is."

On the plus side, the report found the law will cover more than 32 million currently uninsured Americans when fully phased in. And some states ? including New York and Massachusetts ? will see double-digit declines in costs for claims in the individual market.

Uncertainty over costs has been a major issue since the law passed three years ago, and remains so just months before a big push to cover the uninsured gets rolling Oct. 1. Middle-class households will be able to purchase subsidized private insurance in new marketplaces, while low-income people will be steered to Medicaid and other safety net programs. States are free to accept or reject a Medicaid expansion also offered under the law.

___

AP White House Correspondent Julie Pace contributed to this report.

___

Online:

Society of Actuaries: http://www.soa.org/NewlyInsured/

Source: http://news.yahoo.com/study-health-law-raise-claims-cost-32-percent-070021624--finance.html

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